Compound reference
SS-31
Mitochondria-targeted tetrapeptide · Updated
A four-amino-acid peptide studied for its association with cardiolipin, a lipid of the inner mitochondrial membrane.
Identity
- Sequence
- Pending
- Molecular formula
- Pending
- Molecular weight
- Pending
- CAS number
- Pending
Marked pending rather than filled in from a secondary source. These figures will be published when they come from our own analysis, so that this page and the certificates agree.
Published research areas
Fields in which this compound appears in the published literature. These describe where the research sits, not what it concluded.
- Cardiolipin binding
- The mechanism most of the structural literature examines, and what distinguishes this compound from other short peptides.
- Mitochondrial function
- Investigated in cell and animal models examining mitochondrial bioenergetics.
- Structural and biophysical work
- Four residues makes it small enough for detailed conformational study, including in membrane-mimetic systems.
What the analysis should cover
- Identity by mass spectrometry. At four residues the mass measurement is unambiguous, which makes its absence from a certificate harder to excuse rather than easier.
- Purity by HPLC with the chromatogram reproduced, and method conditions stated — very short peptides are weakly retained, so the gradient shapes the number.
- Net peptide content. Short sequences carry proportionally more counterion mass, so the gap between weighed mass and peptide mass is wider here than for a large peptide.
- Salt form and residual counterion, for the same reason.
How to read a certificate of analysis covers what each of these measurements establishes.
Handling and stability
- Supplied freeze-dried and sealed.
- Residual moisture is the best single predictor of how long sealed material keeps.
- Stored cold, dry and dark in the container as supplied.
Why peptides ship freeze-dried sets out the reasoning behind these conditions.
Supplied by us
A mitochondria-targeted tetrapeptide, freeze-dried and sealed in a 10mg vial. Studied in cardiolipin-binding and mitochondrial-function research, and suited to quantitative assay and structural work. Every lot ships with its own certificate of analysis.
View SS-31